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Mid-infrared (MIR) spectroscopy is one of the most powerful methods for analyzing liquids at the molecular level. By detecting the specific vibrational “fingerprints” of chemical bonds, MIR spectroscopy reveals the composition, concentration, and dynamics of liquid mixtures — from solvents and polymers to biological fluids.
When combined with Attenuated Total Reflection (ATR) probes, MIR analysis becomes even more versatile. ATR enables direct in-situ measurements, eliminating the need for sample preparation and allowing precise monitoring of liquids under real-world conditions.
Discover the Power of Real-Time Liquid Analysis
NLIR’s mid-infrared spectrometer powers inline liquid measurements with fiber-coupled ATR probe.
Alcohol content measurements with art photonics ATR probe
In collaboration with art photonics, NLIR demonstrates real-time monitoring of ethanol–water mixtures using an ATR-probe setup. The experiment shows that the MIDWAVE Spectrometer captures subtle variations in the O–H and C–H stretching regions within milliseconds, allowing continuous tracking of concentration changes.
Such a setup is ideal for:
Solvent composition tracking in chemical synthesis
Process control in pharmaceutical and food industries
Quality control in fuel and lubricant production
Research applications requiring fast, accurate spectral feedback
In this video, we have measured 3 different types of alcohol using art photonics ATR probe, NLIR’s MIDWAVE Spectrometer and FIBER Light Source. When dipped into a liquid, the ATR probe facilitates interaction between the mid-infrared light and the liquid, and the light is subsequently guided to the spectrometer. The spectrometer captures spectra every 50 milliseconds, and each spectrum is averaged 10 times, clearly showing the absorption features of the liquid on screen.
Perform liquid measurements with inline ATR Measurement System
ATR Measurement System combined with
MIDWAVE Spectrometer
Read out absorption spectra from a liquid in milliseconds
ATR Measurement System combined with
FIBER Light Source
Get infrared light to your sample in a fiber
ATR Measurement System combined with
Fiber-Coupled ATR Probe
Monitor liquid composition reaction in real time
Let's Collaborate
Combining our state-of-the-art probes, and NLIR’s mid-infrared spectrometers, we can solve the most complex PAT challenges. Let’s keep pushing the boundaries of real-time chemical analysis!
Dr. Stefanie Foerster, CEO of art photonics
new possibilities for Inline Liquid Measurements
With NLIR’s ultra-fast MIDWAVE Spectrometer and art photonics’ robust ATR fiber probes, you can perform real-time liquid analysis with unmatched speed, sensitivity, and stability. Key benefits include:
Fast, real-time measurements — monitor chemical and physical changes in milliseconds.
No sample preparation required — analyze opaque or strongly absorbing liquids directly.
High chemical specificity — detect molecular “fingerprints” across 2.0 – 5.0 µm range.
Compact & fiber-coupled setup — ideal for lab, pilot, or inline integration.
Vibration-tolerant and room-temperature operation — stable data even in industrial environments.
Together, NLIR and art photonics bring lab-grade spectroscopy directly into process environments — enabling inline monitoring of reaction kinetics, quality control, and formulation studies.
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